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Control of Cardiac Output Quiz

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Which statement best describes how cardiac output is determined under normal physiological conditions?

  1. A The volume of blood remaining in the ventricle after systole
  2. B The difference between systolic and diastolic blood pressure
  3. C The amount of blood ejected from the left ventricle per beat
  4. D The resistance that the ventricles pump against during systole
  5. E The product of heart rate and stroke volume
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Answer: E. The product of heart rate and stroke volume

See Cardiac Output. Cardiac output (E) equals heart rate multiplied by stroke volume. It is the volume pumped by one ventricle per minute, so multiplying beats per minute by millilitres per beat gives millilitres per minute. Stroke volume is the difference between end-diastolic volume, the filled volume before contraction, and end-systolic volume, the blood remaining after ejection. Increasing rate or stroke volume raises output if the other factor is unchanged. In a real heart the factors interact: a very rapid rate can reduce filling time and stroke volume, so a faster pulse does not guarantee more blood flow.

Systolic minus diastolic pressure (B) is pulse pressure, a pressure difference rather than a volume per minute. C gives the amount ejected with one beat, so heart rate is still needed to turn it into output. The load opposing ejection (D) is afterload, which can alter how much blood leaves a ventricle but is not a measure of flow itself. A is end-systolic volume, the blood left behind; subtracting it from the starting filled volume gives stroke volume, not cardiac output without the rate.

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More questions from this set. Start the quiz to answer them and see each explanation.

  1. 1

    Within the physiological filling range of a healthy heart, which statement best describes the Frank-Starling law?

  2. 2

    Which mechanism best explains how increased sympathetic nervous system activity raises heart rate?

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