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Cells and Components of the Nervous System Quiz
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Which type of glial cell is primarily responsible for forming myelin around axons in the central nervous system?
- A Astrocytes You picked ✕
- B Schwann cells You picked ✕
- C Oligodendrocytes You picked ✓
- D Microglia You picked ✕
- E Ependymal cells You picked ✕
Correct!
Incorrect
The answer is C: Oligodendrocytes
Explanation
Why C is correct
See Oligodendrocytes. Option C is correct. Glia are the supporting cells of the nervous system, and the oligodendrocyte is the glial cell that makes myelin in the brain and spinal cord (the central nervous system). Myelin is a fatty insulating layer wrapped around an axon (the long, thin cable of a neurone that carries electrical signals away from the cell body). It forces the electrical impulse to jump along the axon rather than creep along it, which makes conduction much faster. A single oligodendrocyte puts out a few branches (its name means 'cell of a few branches') and each branch wraps myelin around a segment of a different axon. In the peripheral nervous system (the nerves outside the brain and spinal cord) the same job is done by Schwann cells, but there each cell wraps only one segment of one axon. Loss of CNS myelin is the basis of multiple sclerosis. Memory aid: oligodendrocytes work in the central nervous system, while Schwann cells work out in the peripheral nerves.
- Cell: The oligodendrocyte makes myelin in the brain and spinal cord.
- Myelin: A fatty insulating layer that makes impulses jump along the axon, so conduction is much faster.
- Contrast: In the peripheral nervous system Schwann cells do the same job, but each wraps only one segment of one axon.
Why the other options are incorrect
- A. Astrocytes: Astrocytes are star-shaped support cells that buffer potassium, recycle neurotransmitters and help form the blood-brain barrier. They do not make myelin. They would be the answer to a question about maintaining the ionic environment. Your answer
- B. Schwann cells: Schwann cells do produce myelin, but only for peripheral nerves outside the brain and spinal cord. This is the classic trap, and they would be correct if the question asked about the peripheral nervous system. Your answer
- D. Microglia: Microglia are the immune cells of the central nervous system. They engulf debris and microbes and play no part in forming myelin. They would be right for a question about immune defence in the brain. Your answer
- E. Ependymal cells: Ependymal cells line the ventricles and help to make and move cerebrospinal fluid. They are not involved in insulating axons. They would be right for a question about the lining of the ventricles. Your answer
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1
Which CNS cell type is primarily responsible for buffering extracellular potassium and clearing excess glutamate from synapses to prevent excitotoxicity?
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2
Which feature is most responsible for the low permeability of the blood-brain barrier to water-soluble substances?
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