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Malignant Breast Disease Quiz
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A 55-year-old woman with a 1.5 cm unifocal invasive ductal carcinoma is choosing primary surgery. She wants to preserve as much of her breast as possible. Which operation is the most appropriate definitive local treatment?
- A Microdochectomy You picked ✕
- B Mammotome vacuum-assisted excision biopsy You picked ✕
- C Nipple-sparing mastectomy You picked ✕
- D Wide local excision You picked ✓
- E Radial scar excision You picked ✕
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Incorrect
The answer is D: Wide local excision
Explanation
Why D is correct
See Invasive Carcinoma. Option D is correct. Breast-conserving surgery removes only the area of the breast that contains cancer, and it is also called a lumpectomy or wide local excision. The surgeon removes the tumour together with a rim of surrounding normal breast tissue, called the margin. The margin matters because cancer cells can extend beyond what can be seen or felt, and the pathologist examines the edge of the removed tissue under the microscope. If the margins are clear of tumour (negative margins), the cancer is considered completely excised. This keeps most of the breast. Whether it is suitable depends on the size and spread of the tumour in relation to the breast, as well as the patient's wishes and other clinical factors, and a mastectomy, the removal of the whole breast, is the alternative. Treating the lymph nodes in the armpit is a separate part of the operation and cannot replace removing the tumour in the breast. Memory aid: lump-ectomy removes the lump and a margin; mast-ectomy removes the breast.
- Operation: breast-conserving surgery (lumpectomy or wide local excision) removes the tumour with a rim of normal tissue.
- Margins: clear margins mean the cancer is completely excised.
- Alternative: mastectomy removes the whole breast.
Why the other options are incorrect
- A. Microdochectomy: Microdochectomy excises a single affected lactiferous duct and is used for conditions such as persistent nipple discharge, not for removing a primary breast cancer with a margin. Your answer
- B. Mammotome vacuum-assisted excision biopsy: This is a percutaneous biopsy device used to sample or remove benign breast lesions; it is not the definitive surgical treatment for an invasive carcinoma. Your answer
- C. Nipple-sparing mastectomy: Nipple-sparing mastectomy removes the breast parenchyma while preserving the nipple-areola skin; it does not conserve most of the breast tissue, so it is not the breast-conserving treatment described. Your answer
- E. Radial scar excision: A radial scar is a benign breast lesion; excising it is not the operation for a known invasive breast cancer, and the option confuses benign breast pathology with cancer surgery. Your answer
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More questions from this set. Start the quiz to answer them and see each explanation.
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1
Which statement best describes ductal carcinoma in situ (DCIS) of the breast?
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2
Which mechanism best explains the increased oestrogen exposure that links obesity to breast cancer risk after menopause?
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